College football odds: Penn State, Notre Dame among 10 best bets for perfect regular seasons in 2025

In college football’s playoff era, only five programs have notched perfect seasons en route to a national championship with Michigan being the most recent in 2023. But now, the parity playoff expansion has brought to the sport — and the possibility of a team playing as many as 16 games on their way to the title game — the likelihood of an unblemished campaign is considerably low.

If it happens during the 2025 season, that team may go down as the new “best-ever.” 

Courtesy of FanDuel Sportsbook, here’s a look at the 10 teams with odds at +800 or better for going unbeaten during the regular season, along with the potential path for each:

Toughest games: vs. Oregon, at Ohio State

Expectations are other-worldly for Penn State this season, perhaps at their highest levels since the 1980s when Joe Paterno won both of the program’s national championships over a five-year stretch. James Franklin’s roster is the best he’s ever had in Happy Valley. He’s averaging 9.6 wins per season since the 2016 campaign with five top-10 finishes during that stretch. If Penn State snaps an eight-game losing skid to the Buckeyes, there’s a great chance the Nittany Lions get to Indianapolis without a loss.

Ohio State Buckeyes…

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