Packers vs. Bears prediction, odds, time, spread: Saturday NFL picks by proven model

Control of the NFC North will be on the line when the Green Bay Packers battle the Chicago Bears on Saturday night. Chicago moved back into first place on Sunday when the Bears defeated the Cleveland Browns 31-3, while Green Bay dropped a 34-26 decision to the Denver Broncos. The Packers (9-4-1), who are 4-0 within the division, are 4-2-1 on the road this season. The Bears (10-4), who are 1-3 in the division, are 5-1 on their home field in 2025. Both teams are dealing with a substantial injury list. Green Bay lost Micah Parsons (knee) for the season last week. The Bears won’t have Rome Odunze (foot) or Luther Burden III (ankle), while D’Andrew Swift (groin) and Cole Kmet (ankle/knee) are among the players listed as questonable. 

Kickoff from Soldier Field in Chicago is set for 8:20 p.m. ET. Chicago is a 1.5-point favorite in the latest Packers vs. Bears odds, while the over/under for total points scored is 46.5 via DraftKings Sportsbook. Before making any Bears vs. Packers picks, check out the NFL predictions from the SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 16 on a 52-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Now, the model has set its sights on Packers vs. Bears. You can visit SportsLine now to see the picks. Here are the FBS college football odds and trends for Bears vs. Packers:

Packers vs. Bears spread

Chicago -1.5 at DraftKings Sportsbook

Packers vs. Bears over/under

46.5 points

Packers vs. Bears …

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