The Week 16 NFL schedule features 16 more games, including several with potential playoff ramifications. One such game is a Saturday NFC North battle between the Green Bay Packers (9-4-1) and the Chicago Bears (10-4). Chicago is favored by 1 point as Jordan Love and the Packers face Caleb Williams and the Bears. Green Bay has won nine of the past 10 meetings, including a 28-21 victory at Lambeau Field two weeks ago. Another key matchup between two contenders is the NFC South matchup between the division co-leading Carolina Panthers and Tampa Bay Buccaneers. The teams are tied with 7-7 records and play each other two times in the final three weeks.
The Buccaneers enter as 3-point road favorites. Sunday’s largest spreads include Raiders vs. Texans (-14.5), Bills (-10.5) vs. Browns and Steelers vs. Lions (-7). Among the worst injuries suffered in Week 15 include Patrick Mahomes (knee) of the Chiefs and Micah Parson (knee) of the Packers, which have affected the NFL spreads in their respective games. Before making any Week 16 NFL picks or NFL score predictions on those games or others, you need to see the NFL against the spread, over/under and money line predictions powered by the self-learning SportsLine AI.
Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine’s Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team’s historical data and then quantitatively evaluating the strength of the opponent’s defense by assigning a numeric value out of 100 called a matchup score. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine’s AI PickBot has hit more than 2,000 4.5- and 5-star prop picks since the start of the 2023 season.
For Week 16 NFL betting, SportsLine AI has evaluated the NFL odds and…
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