The No. 13 Notre Dame Fighting Irish (4-2) are set to host the No. 20 USC Trojans (5-1) on Saturday in one of college football’s most bitter rivalries. The Irish dropped their first two games of the season, but have won four straight since. Notre Dame notched a 36-7 blowout win over N.C. State in its last outing. The Trojans’ lone loss came on the road against Illinois on Sept. 27. USC was dominant in its most recent game, blowing out Michigan 31-13 on Oct. 11. Notre Dame leads the all-time series 52-37-5. Both teams are 3-3 against the spread this season.
Kickoff from Notre Dame Stadium in South Bend is set for 7:30 p.m. ET. The Irish are 10.5-point favorites in the latest Notre Dame vs. USC odds, while the over/under for total points scored is 59.5. Before making any USC vs. Notre Dame picks, make sure you check out what SportsLine college football expert Jimmie Kaylor has to say.
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Kaylor is an NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years.
Kaylor has destroyed the sportsbooks in college football the last two seasons, posting a 252-179-7 record since Week 1 of the 2023 season. His 2024 college football futures picks included Travis Hunter winning the Heisman at 40-1 odds, bringing his net profit up…
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