BYU vs. West Virginia picks, odds, prediction, best bets

A Friday night Big 12 clash features the No. 23 BYU Cougars hosting the West Virginia Mountaineers. The Cougars (4-0, 1-0 in Big 12) are one of 20 FBS teams still undefeated and are coming off a 24-21 victory over Colorado to kick off conference play. West Virginia (2-3, 0-2) has dropped back-to-back Big 12 contests and is coming off a Week 5 defeat to Utah, 48-14. These programs have faced off twice before, with WVU prevailing both times.

Kickoff is at 10:30 p.m. ET from LaVell Edwards Stadium in Provo, Utah. The Cougars are 19.5-point favorites in the latest West Virginia vs. BYU odds, while the over/under for total points scored is 46.5 via SportsLine consensus. Before making any BYU vs. West Virginia picks, check out the college football predictions from the SportsLine Projection Model. 

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The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and is a profitable 37-24 combined on money-line and over/under college football picks since the beginning of 2024. Anybody following its college football betting picks at sportsbooks and on betting sites could have seen strong returns.  

Now, the model has set its sights on West Virginia vs. BYU. You can visit SportsLine now to see the picks. Here are the FBS college football odds and trends for BYU vs. West Virginia:

West Virginia vs. BYU spread

BYU -19.5 at DraftKings Sportsbook

West Virginia vs. BYU over/under

46.5 points

West Virginia vs. BYU money line 

BYU -1316, West Virginia +783

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