Chiefs vs. Texans odds, prediction, spread, line: 2024 NFL Week 16 picks, predictions by expert who is 46-30

Teams already locked into the NFL playoff bracket will clash when the Houston Texans battle the Kansas City Chiefs on Saturday. It will mark the second of three games in a 10-day span for both teams. Houston is coming off a 20-12 win over the Miami Dolphins, while Kansas City defeated the Cleveland Browns, 21-7, in Week 15. The Texans (9-5), who have already clinched the AFC South title, are riding a two-game winning streak. The Chiefs (13-1), who have clinched their ninth consecutive AFC West championship, the second-longest streak in NFL history, have won four in a row. Patrick Mahomes (ankle) was a full participant at practice this week and is active for Kansas City. Chiefs offensive tackle D.J. Humphries (hamstring) is inactive.

Kickoff from GEHA Field at Arrowhead Stadium in Kansas City, Mo., is set for 1 p.m. ET. Kansas City is a 3.5-point favorite in the latest Texans vs. Chiefs odds, while the over/under for total points scored is 42.5. Kansas City is the -186 favorite (risk $186 to win $100) on the money line. Before locking in any Chiefs vs. Texans picks, make sure to check out the NFL predictions and betting advice from the SportsLine expert Larry Hartstein, considering his mastery of picks involving Houston.

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed working for Pro Football Focus. He tied for 52nd place (out of 1,598 entries) in the 2022 Westgate Las Vegas SuperContest, going 53-34-3 ATS. Hartstein’s weekly Vegas contest selections form the basis of his NFL best bets column, which is 79-48-2 (62.2%, +25.95 units) since its inception in 2022. He’s also an amazing 46-30-4 (+1299) on his last 80 NFL picks involving the Texans. Anyone following at sportsbooks and on betting apps has seen huge returns.

Now, Hartstein has locked in on Texans vs. Chiefs and just revealed his coveted…

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