Self-learning AI reveals NFL against the spread, over-under, money-line picks for each 2024 Week 3 game

Chicago’s defense has been disruptive through its first two games, racking up four takeaways and six sacks with a pressure rate of 31%. The Bears also have one of the best third-down conversion rates defensively at 25%, causing them to go under the total in their first two contests. They head to Indianapolis on Sunday during the Week 3 NFL schedule in a game that has a total of 43.5 in the latest Week 3 NFL odds. Two of the league’s youngest quarterbacks will go head-to-head, Anthony Richardson (Colts) and Caleb Williams (Bears), but should you expect a low-scoring game when you place your Week 3 NFL against the spread picks?

Richardson has thrown four interceptions and fumbled twice in his first two outings, while Williams was sacked seven times by the Texans last week. Williams has the better defense backing him up, but the Colts are 1-point home favorites in the Week 3 NFL odds. Before you make any Week 3 NFL picks, you need to see the NFL against the spread, over-under, and money line predictions powered by SportsLine AI.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine’s Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team’s historical data and then quantitatively evaluating the strength of the opponent’s defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.

In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the…

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